KNI Grades
How does KNI score a supplement?
Every ingredient is scored on the same 100-point, five-axis rubric, and the full methodology is public. Grades run S, A, B and C. The governing rule is that only what is disclosed and evidenced counts: a product withholding purity, dose or test results cannot reach a top grade.
Rubric
Axes and weights
- ① Effective dose30
Does the actual daily intake reach the dose range used in human studies — not the number in the product name?
- ② Purity & impurity testing25
Published purity figures plus third-party COA, with verifiable impurity and heavy-metal testing.
- ③ Manufacturing & safety certification20
cGMP/FDA-registered facilities, ingredient-specific certifications (Self-GRAS, NSF), and toxicology data (GLP).
- ④ Raw-material grade15
Named ingredient brand — whether a verified supplier such as Creapure®, Uthever® or Setria® is used.
- ⑤ Information transparency10
Full ingredient and dose disclosure, convertible labelling, and claims free of exaggeration.
- Total100
What does each axis check, ingredient by ingredient?
The weighted axes apply identically to every ingredient, but what verifies each axis differs by ingredient. Purity means creatinine ppm for creatine and β-isomer HPLC testing for NMN. Below is every check currently in force.
① Effective dose /30
- —Clinically studied dose (≥250 mg/day)
- —3–5 g daily-dose design
- —Actual GSH content disclosed
- —Actual berberine HCl content
② Purity & impurity testing /25
- —β-isomer, ≥99% purity
- —Third-party verified content
- —Impurity testing (DCD, DHT)
- —Third-party test results
- —≥97% standardisation with lot testing
③ Manufacturing & safety certification /20
- —Stabilized form & moisture-proof packaging
- —cGMP manufacture + independent certification
- —Third-party doping certification (for athletes)
- —Absorption design
- —cGMP / NSF-certified facility
④ Raw-material grade /15
- —Verified raw material (99.9%+ purity)
- —Named fermentation-derived brand
- —Absorption-engineered raw material
⑤ Information transparency /10
- —Regulation-compliant supply chain (NDI)
- —Monohydrate form
- —Single ingredient (no unnecessary blends)
- —Reduced form (GSH) stated
- —Contraindication labelling
Cut-offs
Grade cut-offs
- S
85 and above
Meets every criterion — the pick if you choose by standard.
- A
70–84
Core criteria met; some certification or supplier data unverified.
- B
55–69
Baseline met, but under-dosed or test results undisclosed.
- C
Below 55
Under-dosed or undisclosed specs — includes unverifiable products.
Operating principles
- 1The full weighting and methodology are published.
- 2All figures come from official retailer listings and published test reports (COAs), with the data date stated.
- 3Products are re-scored quarterly; when a grade changes, the reason is published.
- 4KNI and EGA share ownership and management. EGA products are scored using the published weights and cut-offs alongside other products.
- 5Named listings are limited to overseas brands and to top-tier (S/A) domestic products whose evidence — ingredient brand, certifications and test reports — is publicly verifiable. All other domestic products appear as a category.
- 6The lowest, unverifiable tier (grade C) appears as a category rather than by name.
Current grades by ingredient
As of 2026-08 · Based on official retailer listings and published test reports
NMNLongevity anchor
- SEGA NMN Daily Regenerator92/100
- SRokit America NMN + Pterostilbene90/100
- AProHealth NMN Pro (Uthever®)78/100
- BDouble Wood NMN61/100
- CUnbranded import / marketplace NMN10/100
CreatineBrain & cognition
- SHealthy Origins Performance Creatine92/100
- ANutricost Creatine75/100
- BNOW Foods Micronized Creatine64/100
- CPre-workout / booster blends13/100
GlutathioneAntioxidant & inner beauty
- SPure Encapsulations Liposomal Glutathione91/100
- AQuicksilver Scientific Liposomal72/100
- AJarrow Reduced Glutathione 500 mg72/100
- BGeneric GSH tablets (unbranded import)55/100
- C"Contains glutathione" gummies, jellies and drinks13/100
BerberineGlycemic & metabolic
- SThorne Berberine (Berbevis®)93/100
- SToniiq Berberine 97%88/100
- ADouble Wood Berberine73/100
- BBulkSupplements Berberine Powder56/100
- C"Contains Coptis extract" diet blends11/100
KNI grades reflect our own published criteria and are not a government or accreditation-body certification. KNI and EGA share ownership and management. We publish the scoring weights and cut-offs and apply the same criteria to every product.